What is the distance between Earth and Pluto in miles?
It varies. The average distance is nearly the average distance of Pluto, from the Sun, 5906.4 million km = 3670.2 M miles. Interestingly this average is the same, for every other inner planet.
The distance between an inner planet and outer planet varies from (outer perihelion - inner aphelion) and (outer aphelion + inner perihelion), nearly. The average is as stated.