What is the order of Synaptic Transmission?

1 Answer
May 25, 2017

Answer:

  1. Neurotransmitter synthesis
  2. Packaging
  3. Release
  4. Binding
  5. Stopping the chemical signal

Explanation:

Electrical information is conducted through the body along neurons. But neurons are not infinitely long (although some can be pretty long and measure above 1 m in length) and they “synapse” on each other.

The problem is that at the point of synaptic junction there is a “gap” between the first neuron and the subsequent one. This gap is called the synaptic cleft (it’s between #10" nm"# and #20" nm"# large).

The electrical signal cannot “jump” over that gap. Instead, at the point of synaptic junction between two neurons, the electrical signal is “translated” into a chemical message (the neurotransmitter) by the presynaptic neuron (at the presynaptic terminal) – Step 1 & 2.

That chemical diffuses (“swims”) across the synaptic cleft until it reaches the other neuron – Step 2 & 3.

The other neuron then “translates” the chemical signal back into an electrical one – Step 3 & 4.

The chemical message is degraded – Step 5.

This “new” electrical message can now travel down the neuron until it reaches a new synaptic junction.