What is the phosphodiester bond and how is it drawn?

1 Answer
Apr 17, 2018

See Below


Nucleotide Monophosphates, NMPs, are nucleosides that have 1 phosphate group. Here is GMP.
enter image source here

All simple nucleotides have this phosphoester bond.

When one nucleotide makes a linkage with another nucleotide, the phosphate group (which already has 1 ester bond) makes a 2nd ester bond. This becomes a phosphodiester bond.

In the picture below, the phosphate group has one ester bond to the nucleotide below, and one ester bond to the nucleotide above. This is the phosphodiester bond.
enter image source here