When 1 mol of NaBH4 is used to reduce ketone, how many moles of hydride is used?
Potentially 4. In practice, these reducing agents are often used 1:1.
The common metal hydride reducing agents, lithium aluminum hydride,
When you are doing large scale reductions (i.e. when you are trying to reduce
As a rule of thumb, when doing large reductions, it is often practical to assume that the hydride transfer reagent will deliver at least 3 equiv hydride. This makes the workup a lot more controllable.