Question

Which of the four bases is present in a higher percentage in an eukaryotic telomere?

Answer 1

`T TAGCG` is repeated many times in human telomeres.

On the lagging strand of parent DNA in DNA replication, there is a length unreplicated because it's "too short" to make another Okazaki fragment.

As we know, replication on the lagging strand is dictated by Okazaki fragment polymerization by RNA polymerase in the `5' to 3'` direction.

A good inference based on these interactions is the fact that chromosomes shorten as a function of the number of times replicated`""^1`.

References:

1. Allsopp, R. C., Vaziri, H., Patterson, C., Goldstein, S., Younglai, E. V., Futcher, A. B., . . . Harley, C. B. (1992). Telomere length predicts replicative capacity of human fibroblasts. Proceedings of the National Academy of Sciences, 89(21), 10114-10118. doi:10.1073/pnas.89.21.10114