Why is X inactivation necessary?
1 Answer
Feb 3, 2017
As nearly all female mammals have two X chromosomes , X inactivation prevents them from having twice as many X chromosome gene products as males.
Explanation:
The inactive X chromosome is silenced by its being packaged in such a way that it has a transcriptionally inactive structure called heterochromatin.
Inactivation occurs on a cellular level ,resulting in a mosaic expression , in which patches of cells have an inactive maternal X chromosome, while others have an inactive paternal chromosome.
