Question #45441

1 Answer
Apr 3, 2017

2 #CO_2# are produced when the Kreb cycle operates once

Explanation:

![https://useruploads.socratic.org/LsOzbMuCQgm93CaPSNQz_5621144.jpg)

As the diagram shows, 2 #CO_2# molecules are released when #isocitrate# is oxidized and subsequently decarboxylated. The first part of this 2 step process is aided by the enzyme #"isocitrate dehydrogenase"# and the coenzyme, #NAD+#.

#"alpha ketoglutarate"# then proceeds to undergo a reaction with the help of #"alpha ketoglutarate dehydrogenase complex"#, #NAD+#, #TPP#, #"lipoic acid"#, and #Mg^2+#, to become #"succinyl-CoA"#