How do you use the chain rule to differentiate #y=(x^2+3x)^(-1/2)#? Calculus Basic Differentiation Rules Chain Rule 1 Answer James May 14, 2018 #dy/dx=[-(2x+3)*(x^2+3x)^(-3/2)]/2# Explanation: show below #y=(x^2+3x)^(-1/2)# let suppose: #u=x^2+3x# #(du)/dx=2x+3# #y=u^(-1/2)# #dy/(du)=-1/2*u^(-3/2)# #dy/dx=(du)/dx*dy/(du)# #dy/dx=(2x+3)*(-1/2*u^(-3/2))# #dy/dx=[-(2x+3)*u^(-3/2)]/2# #dy/dx=[-(2x+3)*(x^2+3x)^(-3/2)]/2# Answer link Related questions What is the Chain Rule for derivatives? How do you find the derivative of #y= 6cos(x^2)# ? How do you find the derivative of #y=6 cos(x^3+3)# ? How do you find the derivative of #y=e^(x^2)# ? How do you find the derivative of #y=ln(sin(x))# ? How do you find the derivative of #y=ln(e^x+3)# ? How do you find the derivative of #y=tan(5x)# ? How do you find the derivative of #y= (4x-x^2)^10# ? How do you find the derivative of #y= (x^2+3x+5)^(1/4)# ? How do you find the derivative of #y= ((1+x)/(1-x))^3# ? See all questions in Chain Rule Impact of this question 2330 views around the world You can reuse this answer Creative Commons License