Most of the noble gases will not react with other elements.
These noble gases will not react because they have very stable electron configurations and do not need to add or lose electrons to form compounds to achieve more stable electron arrangements.
Kr , Xe and Rn may react with halogens, specifically fluorine. F is the most reactive halogen. Compounds of these noble gases are exceptions to the octet rule. This means that the outer shell of the noble gas will have more than 8 electrons.
Here is a video which discusses the topic of chemical periodicity. Video from: Noel Pauller
Hope this helps!