# How does "acetone" differ from "propionaldehyde"?

Jul 24, 2017

You gots ${H}_{3} C - C {H}_{2} C \left(= O\right) H$ versus ${H}_{3} C - C \left(= O\right) C {H}_{3}$
Now both molecules have a molecular formula of ${C}_{3} {H}_{6} O$, and both isomers have a carbonyl functionality. However, the connectivity is different: we have an internal carbonyl for the ketone, and a terminal carbonyl for the aldehyde.
The chemistry of these structural isomers would be similar. However, propanal or propionaldehyde, because the carbonyl is at the end of the chain, would be more reactive than the ketone, whose carbonyl is at ${C}_{2}$......this is a steric effect.
Would ""^1H $\text{NMR spectroscopy}$ be a good means to differentiate the two isomers?