What chemical starts off the chain reaction in the initiation step of an anti-markovnikov radical addition?
The initiator in a free radical addition reaction is a substance that decomposes into free radicals under mild conditions.
An initiator should have bonds with low dissociation energies (e.g.
Common initiators are:
Azo compounds (
AIBN (azo-bis-isobutyronitrile) is a convenient free radical initiator because it decomposes at relatively low temperatures.
Two common peroxide initiators are
(a) Di-t-butyl peroxide
(b) Benzoyl peroxide