What do you get when you react benzaldehyde and acetophenone with a base?

1 Answer
Nov 20, 2015

I'm assuming with heat involved?

You would get the product of an aldol condensation. Specifically for your case, a chalcone.

The mechanism is:

Can you analogize and draw the mechanism for your compounds? This seems like a question related to a lab, and you should be able to do it from here.

CHALLENGE: Do you know why, conformationally, the second half of the reaction does not involve #beta#-elimination of the hydroxyl on the first step, but the generation of an enolate beforehand instead?