The vertex form of quadratic equation is y=a(x-h)^2+k and its vertex is (h,k) and axis of symmetry is x-h=0.
Hence we should first convert y=(x^2+21x+22)/16 into vertex form.
y=(x^2+21x+22)/16
= 1/16(x^2+2xx21/2xx x+(21/2)^2-(21/2)^2+22)
= 1/16(x+21/2)^2-441/64+22/16
= 1/16(x+21/2)^2-(441-88)/64
= 1/16(x-(-21/2))^2-353/64
Therefore, its vertex is (-21/2,-353/64) and axis of symmetry is x-(-353/64)=0 or x+353/64=0.
y-intercept can be found by putting x=0 and x-intercept can be found by putting y=0.
Hence y-intercept is 22/16=11/8
and x-intercept are given by using quadratic formula on x^2+21x+22=0 i.e. x=(-21+-sqrt(21^2-4xx22))/2=(-21+-sqrt353)/2 i.e. -1.1 and -19.9.
While domain is (-oo,oo), range is [-353,64,oo)
graph{(y-(x^2+21x+22)/16)=0 [-27.33, 12.67, -10.16, 9.84]}