Let's factorise the denominator
x^2-5x+6=(x+1)(x-6)
Let f(x)=(x+3)/((x+1)(x-6))
The domain of f(x) is D_f(x)=RR-{-1,6}
Now, we can build the sign chart
color(white)(aaaa)xcolor(white)(aaaa)-oocolor(white)(aaaa)-3color(white)(aaaaaa)-1color(white)(aaaaaaaaa)6color(white)(aaaaaa)+oo
color(white)(aaaa)x+3color(white)(aaaaaa)-color(white)(aaaa)+color(white)(aaa)||color(white)(aaaa)+color(white)(aaa)||color(white)(aaaa)+
color(white)(aaaa)x+1color(white)(aaaaaa)-color(white)(aaaa)-color(white)(aaa)||color(white)(aaaa)+color(white)(aaa)||color(white)(aaaa)+
color(white)(aaaa)x-6color(white)(aaaaaa)-color(white)(aaaa)-color(white)(aaa)||color(white)(aaaa)-color(white)(aaa)||color(white)(aaaa)+
color(white)(aaaa)f(x)color(white)(aaaaaaa)-color(white)(aaaa)+color(white)(aaa)||color(white)(aaaa)-color(white)(aaa)||color(white)(aaaa)+
Therefore,
f(x)<=0 when x in ]-oo,-3] uu ]-1,6[