How could you improve the yield of diels alder reactions?
I can think of four possible methods.
1. Increase the temperature
Although heat is not often required in Diels-Alder reactions, increasing the temperature usually improves the yield.
2. Increase the amount of catalyst
You usually use a catalyst to increase the rate of a reaction.
Using a molar ratio of 10% catalyst often gives a large increase in both the selectivity and the yield of the reaction.
3. Do the reaction in LPDE
Many Diels-Alder reactions using
4. Do the reaction in a microwave
Many common Diels-Alder reactions give better yields and are effectively complete after 5 to 10 min in the microwave at 125 °C to 150 °C.